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Tohoku Univ. Technology:Dynamic deformable phantom, method and program for preparing radiation treatment plan:T16-069

Accuracy evaluation of dose aggregation using image deformation technology is possible

 In recent years, the development of irradiation equipment capable of pinpoint irradiation by accurately grasping the position of the cancer affected area has advanced, making it possible to perform highly accurate treatment. Deformable image registration (DIR), which is the alignment using images obtained by 4D-CT, etc. is often used to prepare the treatment plan. Although the use of DIR is expected to expand in the future, the accuracy of images obtained as a result of DIR and the accuracy of the calculated combined dose remain controversial.   To solve the above problem, the inventors devised a Dynamic deformable phantom that can perform complex movements as if it were a patient's organ, and can insert acrylic markers and dosimeters.  The present invention makes it possible to evaluate the combined dose distribution using image deformation techniques. It is possible to accurately evaluate the dose distribution in cases where a treatment plan is to be reformulated or where some irradiation fields overlap between past and present treatments. These effects are expected to improve treatment outcomes and reduce side effects.

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Tohoku Univ. Technology:Deformable image registration adjustment support device, support method and program:T19-009

Reduce the effort of the coordinator

In recent years, deformable image registration (DIR) has been used to create radiotherapy treatment plans in medical practice. The accuracy of DIR is evaluated by the small difference between the image after deformation by DIR and the image obtained by imaging. To evaluate this, the common point (landmark point) between two images is found and compared. However, since the deformation by DIR is a non-rigid deformation, the relative positional relationship of each position such as the distance between the vertices of the image to be mapped to the image and the angle of the vertices is not necessarily preserved. Therefore, it is necessary for the coordinator to make a judgment based on his/her experience, and there is a problem that the burden on the coordinator is large.   To solve this problem, the inventors developed a phantom in which a rod simulating a tumor and an organ can be inserted, and an algorithm for verifying the accuracy of DIR using this phantom, and completed the present invention.  In addition to being able to reproduce various shape changes easily by replacing the rod, the phantom of the present invention can automatically set thousands of landmark points by applying position information at the time of medical image acquisition, and can automate all DIR accuracy evaluations.

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